What is SINALGAN®?

SINALGAN® is a food supplement based on N-Acetyl-D-Glucosamine, Chondroitin sulphate, Methylsulfonylmethane (MSM), Boswellia serrata, Silica (SiO2) and Vitamin C (100% RDA).

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N-ACETYL-GLUCOSAMINE (NAG)

Is one of the most important precursors for the synthesis of Glycosaminoglycans (GAGs), the main constituents, together with Collagen, of articular cartilage, tendons and ligaments. NAG is also a basic component of Hyaluronic Acid, one of the most represented GAGs in the articular cartilage. Several studies have shown that the administration of NAG in patients with Osteoarthritis could slow down the cartilage degradation process, “integrate” the loss of articular cartilage and, at the same time, have a moderate anti-inflammatory effect.

CHONDROITIN SULPHATE

Is another class of Glycosaminoglycan expressed in the articular cartilage. Chondroitin Sulphate contributes to the elasticity of cartilage and inhibits its degradation by lytic enzymes (Elastase and Hyaluronidase). Current scientific evidence agrees on the effect of Chondroitin Sulphate and N-Acetyl-Glucosamine in improving joint function in patients with Oteoarthritis

METHYLSULFONYLMETHANE (MSM)

Is the natural form of organic sulfur. Because of MSM’s sulfur content, it is used by the body to maintain normal connective tissues. Moreover, MSM provides a natural anti-inflammatory action (NO GASTRIC DAMAGE) as it reduces the production of pro-inflammatory cytokines and lytic enzymes that destroy articular cartilage. For these reasons MSM supplement could contribute to reduce joint pain and stiffness in patients with Osteoarthritis.

BOSWELLIA SERRATA

Is a plant widely spread in Southeast Asia, especially in India. Boswellic Acid are specific inhibitors of 5-lipoxygenase, the key enzyme for leukotriene biosynthesis (important mediators in the inflammatory process). The selective inhibition of 5-lipoxygenase makes the anti-inflammatory action of Boswellia serrata particularly useful for therapeutic purposes as it does not cause gastric damages. Scientific studies have shown that Boswellia serrata helps reduce swelling, pain and stiffness in the joints as well as improving joint mobility.

SILICA (SiO2)

Is the organic form of Silicon. Adequate amount of Silicon in the joints is important to ensure the synthesis of Collagen and Elastin: the former acts as a scaffold which supports cartilage tissues, whereas the latter gives the cartilage its elastic characteristics. Silicon is also important for bone health as it promotes bone mineralization processes.

VITAMIN C (100% RDA)

Is a powerful endogenous antioxidant. Vitamin C contributes to normal collagen formation, necessary for the normal function of bones, cartilage and skin.

What is SINALGAN®?

SINALGAN® is a food supplement based on N-Acetyl-D-Glucosamine, Chondroitin sulphate, Methylsulfonylmethane (MSM), Boswellia serrata, Silica (SiO2) and Vitamin C (100% RDA).

.

N-ACETYL-GLUCOSAMINE (NAG):

is one of the most important precursors for the synthesis of Glycosaminoglycans (GAGs), the main constituents, together with Collagen, of articular cartilage, tendons and ligaments. NAG is also a basic component of Hyaluronic Acid, one of the most represented GAGs in the articular cartilage. Several studies have shown that the administration of NAG in patients with Osteoarthritis could slow down the cartilage degradation process, “integrate” the loss of articular cartilage and, at the same time, have a moderate anti-inflammatory effect.

CHONDROITIN SULPHATE

Is another class of Glycosaminoglycan expressed in the articular cartilage. Chondroitin Sulphate contributes to the elasticity of cartilage and inhibits its degradation by lytic enzymes (Elastase and Hyaluronidase). Current scientific evidence agrees on the effect of Chondroitin Sulphate and N-Acetyl-Glucosamine in improving joint function in patients with Oteoarthritis

METHYLSULFONYLMETHANE (MSM)

is the natural form of organic sulfur. Because of MSM’s sulfur content, it is used by the body to maintain normal connective tissues. Moreover, MSM provides a natural anti-inflammatory action (NO GASTRIC DAMAGE) as it reduces the production of pro-inflammatory cytokines and lytic enzymes that destroy articular cartilage. For these reasons MSM supplement could contribute to reduce joint pain and stiffness in patients with Osteoarthritis.

BOSWELLIA SERRATA

Is a plant widely spread in Southeast Asia, especially in India. Boswellic Acid are specific inhibitors of 5-lipoxygenase, the key enzyme for leukotriene biosynthesis (important mediators in the inflammatory process). The selective inhibition of 5-lipoxygenase makes the anti-inflammatory action of Boswellia serrata particularly useful for therapeutic purposes as it does not cause gastric damages. Scientific studies have shown that Boswellia serrata helps reduce swelling, pain and stiffness in the joints as well as improving joint mobility.

SILICA (SiO2)

Is the organic form of Silicon. Adequate amount of Silicon in the joints is important to ensure the synthesis of Collagen and Elastin: the former acts as a scaffold which supports cartilage tissues, whereas the latter gives the cartilage its elastic characteristics. Silicon is also important for bone health as it promotes bone mineralization processes.

VITAMIN C (100% RDA)

Is a powerful endogenous antioxidant. Vitamin C contributes to normal collagen formation, necessary for the normal function of bones, cartilage and skin.

Scientific evidence has demonstrated the potential beneficial effects of the active principles contained in SINALGAN® in case of

Scientific evidence has demonstrated the potential beneficial effects of the active principles contained in SINALGAN® in case of

OSTHEOARTHRITIS

(Knees, Hips, Backbone, Shoulders, etc.)

CONDROPATHIES

(Degenerative, Inflammatory, Traumatic)

ARTHRITIS

(Hands, Wrists, Elbows, Knees, Ankles)

OSTHEOARTHRITIS

(Knees, Hips, Backbone, Shoulders, etc.)

CONDROPATHIES

(Degenerative, Inflammatory, Traumatic)

ARTHRITIS

(Hands, Wrists, Elbows, Knees, Ankles)

IN ASSOCIATION WITH THE INTRA-ARTICULAR HYALURONIC ACID INFILTRATIONS

IN ASSOCIATION WITH THE INTRA-ARTICULAR HYALURONIC ACID INFILTRATIONS

HOW TO USE

It is recommended to take one sachet a day, 30 minutes after breakfast/lunch. Pour the contents of the sachet into a glass and then add water. Mix very well for about one minute until completely dissolved. The eventual precipitants in the solution don’t affect the quality of the product but are due to the natural characteristics of its constituents.

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INGREDIENTS

Methylsulfonylmethane, Maltodextrin, N-Acetyl-D-Glucosamine (shellfish), Chondroitin Sulphate, Boswellia (Boswellia serrata Roxb., maltodextrin) dry extract rubber-resin tit. 65% in boswellic acid, Aroma, Citric Acid, Sodium Chloride, Vitamin C (L-Ascorbic Acid), Anti-caking Agents: Silicon Dioxide: Sucralose, Steviol Glycosides; Colouring Agents: E120, E106.

WARNING

Keep out of the sight and reach of children under the age of three. Do not take more than the daily allowance specified on the label. Food supplements must not be considered as a substitute for a varied balanced diet and a healthy lifestyle. Do not use the product if the packet has been opened or is damaged in any way. Use is not recommended in cases of overt hypersensitivity to one or more ingredients contained in the product. Considering the nature of the ingredients the appearance of the product could vary from batch to batch, but this does not imply that the quality is compromised.

PACKET CONTENTS

20 single-dose Sachets

FAQ

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HOW TO TAKE SINALGAN?

It is recommended to take one sachet a day, 30 minutes after breakfast/lunch. Pour the contents of the sachet into a glass and then add water. Mix very well for about one minute until completely dissolved. The eventual precipitants in the solution don’t affect the quality of the product but are due to the natural characteristics of its constituents.

FOR HOW LONG CAN SINALGAN BE TAKEN?

It is recommended to take SINALGAN® for at least two consecutive months for better efficacy and long-term results.

ARE THERE ANY SIDE EFFECTS?

Do not take SINALGAN® in case of overt hypersensitivity to one or more ingredients or any other component of this food supplement. Do not take during pregnancy and lactation. Do not administer to children under the age of 12. Do not take if you are allergic or intolerant to Shellfish.

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IS A DOCTOR’S PRESCRIPTION REQUIRED?

SINALGAN® is a food supplement therefore a prescription is not required.

CAN SINALGAN BE TAKEN WITH OTHER DRUGS?

Do not take SINALGAN ® if you are undergoing treatment with oral anticoagulants (Warfarin/Coumadin®). SINALGAN ® can be taken by patients being treated with heparin or new- generation Anticoagulants.

.

HOW TO TAKE SINALGAN?

It is recommended to take one sachet a day, 30 minutes after breakfast/lunch. Pour the contents of the sachet into a glass and then add water. Mix very well for about one minute until completely dissolved. The eventual precipitants in the solution don’t affect the quality of the product but are due to the natural characteristics of its constituents.

FOR HOW LONG CAN SINALGAN BE TAKEN?

It is recommended to take SINALGAN® for at least two consecutive months for better efficacy and long-term results.

ARE THERE ANY SIDE EFFECTS?

Do not take SINALGAN® in case of overt hypersensitivity to one or more ingredients or any other component of this food supplement. Do not take during pregnancy and lactation. Do not administer to children under the age of 12. Do not take if you are allergic or intolerant to Shellfish.

.

IS A DOCTOR’S PRESCRIPTION REQUIRED?

SINALGAN ® is a food supplement therefore a prescription is not required.

CAN SINALGAN BE TAKEN WITH OTHER DRUGS?

Do not take SINALGAN ® if you are undergoing treatment with oral anticoagulants (Warfarin/Coumadin®). SINALGAN ® can be taken by patients being treated with heparin or new- generation Anticoagulants.

N-Acetyl-D-Glucosamine: a molecule with many primates!

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