What is COMBINERV®?
COMBINERV® is a food supplement based on Acetyl-L-Carnitine M.A.T.R.I.S.®, Superoxide Dismutase GliSODin® and Vitamin B12 (100% NRV).
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ACETYL-L-CARNITINE M.A.T.R.I.S.®
A small endogenous molecule derived from L-carnitine acetylation process. Several studies have demonstrated two important roles of ALC in the organism: it acts as a neuroprotective factor, protecting nerve cells from damage induced by free radicals (ROS), and as a neurotrophic factor, favoring the reparative processes of the nerve. The patented M.A.T.R.I.S.® formulation enables controlled release of the active ingredient, ensuring greater bioavailability and prolonged absorption over time.
URIDINE
A pyrimidine nucleoside composed of ribose and uracil. Numerous studies have highlighted its ability to stimulate neurogenesis and axonal regeneration, significantly contributing to the repair of damaged nerves. Additionally, uridine promotes the synthesis of phospholipids and glycoproteins, key components for the regeneration of the myelin sheath and proper nerve cell function.
SUPEROXIDE DISMUTASE GliSODin®
Another endogenous enzyme with antioxidant action. It is the body’s first line of defense against damage induced by free radicals (ROS). GliSODin® is a patented product containing vegetable origin Superoxide dismutase (SOD) encapsulated with the Gliadin protein, which allows the passage gastric without undergoing degradation, and the achievement of the gut where it begins its biological activity.
VITAMIN B12 (100% RDA)
Adequate amounts of Vitamin B12 are essential for the maintenance of myelin, the protective coating around nerves of the peripheral nervous system. This sheath allows electrical impulses to transmit quickly and efficiently along the nerve cells (Vitamin B12 supports the normal function of the nervous system).
What is COMBINERV®?
COMBINERV® is a food supplement based on Alpha Lipoic Acid M.A.T.R.I.S.® Retard, Superoxide Dismutase GliSODin®, N-Acetyl-L-Carnitine and Vitamin B12 (100% RDA).
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ACETYL-L-CARNITINE M.A.T.R.I.S.® RETARD
A small endogenous molecule derived from L-carnitine acetylation process. Several studies have demonstrated two important roles of ALC in the organism: it acts as a neuroprotective factor, protecting nerve cells from damage induced by free radicals (ROS), and as a neurotrophic factor, favoring the reparative processes of the nerve. The patented M.A.T.R.I.S.® formulation enables controlled release of the active ingredient, ensuring greater bioavailability and prolonged absorption over time.
URIDINE
A pyrimidine nucleoside composed of ribose and uracil. Numerous studies have highlighted its ability to stimulate neurogenesis and axonal regeneration, significantly contributing to the repair of damaged nerves. Additionally, uridine promotes the synthesis of phospholipids and glycoproteins, key components for the regeneration of the myelin sheath and proper nerve cell function.
SUPEROXIDE DISMUTASE GliSODin®
another endogenous enzyme with antioxidant action. It is the body’s first line of defense against damage induced by free radicals (ROS). GliSODin® is a patented product containing vegetable origin Superoxide dismutase (SOD) encapsulated with the Gliadin protein, which allows the passage gastric without undergoing degradation, and the achievement of the gut where it begins its biological activity.
VITAMIN B12 (100% RDA)
Adequate amounts of Vitamin B12 are essential for the maintenance of myelin, the protective coating around nerves of the peripheral nervous system. This sheath allows electrical impulses to transmit quickly and efficiently along the nerve cells (Vitamin B12 supports the normal function of the nervous system).
2 PATENTS IN ONE PRODUCT
Using a medium with the same conditions of the gastric environment, the scientists sampled levels of SOD over time. The antioxidant activity of free SOD was destroyed within about 10 minutes. However, when SOD was protected by Gliadin, its enzymatic activity was preserved. The enzyme was released after about 30 minutes, reaching maximum of its activity after 80 – 100 minutes.
Acetyl-L-Carnitine delivered with M.A.T.R.I.S.® technology may counteract neuropathy more effectively than the free form, thanks to its ability to modulate myelination processes, prevent nerve damage and restore proper neurotrophic support.
Using a medium with the same conditions of the gastric environment, the scientists sampled levels of SOD over time. The antioxidant activity of free SOD was destroyed within about 10 minutes. However, when SOD was protected by Gliadin, its enzymatic activity was preserved. The enzyme was released after about 30 minutes, reaching maximum of its activity after 80 – 100 minutes.
The use of M.A.T.R.I.S.® technology enhances intestinal absorption through controlled and sustained release of the active ingredient over time. This system ensures a delayed absorption peak, gradually modulating the availability of Acetyl-L-Carnitine and optimizing its action at the target site.
Acetyl-L-Carnitine delivered with M.A.T.R.I.S.® technology may counteract neuropathy more effectively than the free form, thanks to its ability to modulate myelination processes, prevent nerve damage and restore proper neurotrophic support.
Scientific evidence has demonstrated the potential beneficial effects of the active principles contained in CombiNERV® in case of:
Scientific evidence has demonstrated the potential beneficial effects of the active principles contained in CombiNERV® in case of:
DIABETIC NEUROPATHY
RADICULOPATHIES
(Cervical, Lubar, etc…)
CANALICULAR SYNDROMES
(Carpal, Ulnarian, Cubital tunnel syndrome)
DIABETIC NEUROPATHY
RADICULOPATHIES
(Cervical, Lumbar, etc…)
CANALICULAR SYNDROMES
(Carpal, Ulnarian, Cubital tunnel syndrome)
DRUG INDUCED NEUROPATHIES
(caused by some anticancer drugs)
NEURALGIA
(Trigeminal Neuralgia, Post-herpetic neuralgia)
TINNITUS AND DIZZINESS
(Neuro-inflammatory causes)
DRUG INDUCED NEUROPATHIES
(caused by some anticancer drugs)
NEURALGIA
(Trigeminal Neuralgia, Post-herpetic neuralgia)
TINNITUS AND DIZZINESS
(Neuro-inflammatory causes)
HOW TO USE
It is recommended to take one tablet a day, regardless of meals.
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INGREDIENTS
L-Acetyl Carnitine Hydrochloride M.A.T.R.I.S.®, Bulking agent: Microcrystalline cellulose; Uridine 5’-monophosphate disodium salt; Anti-caking agents: Silicon dioxide, Magnesium salts of fatty acids, Talc; Coating agents: Polyvinyl alcohol, Talc, Hydroxypropylmethylcellulose, Polyethylene glycol; Glisodin® – SOD from melon fruit (Cucumis melo L., maltodextrin, wheat) Superoxide dismutase 1 IU/g; Cross-linked sodium carboxymethylcellulose; Vitamin B12 (Cyanocobalamin), Colorants: Calcium carbonate, Iron oxides and hydroxides..
WARNING
Do not take more than the daily allowance specified on the label. Keep out of the reach of children under 3. Do not take more than the daily allowance specified on the label. Food supplements must not be considered as a substitute for a varied balanced diet and a healthy lifestyle. Do not use the product if the packet has been opened or is damaged in any way. Use is not recommended in cases of overt hypersensitivity to one or more ingredients contained in the product. Considering the nature of the ingredients the appearance of the product could vary from batch to batch, but this does not imply that the quality is compromised.
PACKET CONTENTS
20 coated tablets
FAQ
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HOW TO TAKE CombiNERV?
It is recommended to take one tablet a day, regardless of meals. You can take CombiNERV® any time of the day, without compromising its effectiveness.
FOR HOW LONG CAN COMBINERV BE TAKEN?
It is recommended to take CombiNERV® for at least two consecutive months for better efficacy and long-term results.
ARE THERE ANY SIDE EFFECTS?
Do not take CombiNERV® in case of overt hypersensitivity to one or more ingredients or any other component of this food supplement.
Do not take during pregnancy and lactation.
Do not administer to children under the age of 12.
Contains GLUTEN: product unsuited for patients with celiac disease. In rare cases lipoic acid can cause hypoglycaemia.
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IS A DOCTOR'S PRESCRIPTION REQUIRED?
CombiNERV® is a food supplement therefore a prescription is not required.
CAN CombiNERV BE TAKEN WITH OTHER DRUGS?
CombiNERV® can be taken with other drugs without any side effects.
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HOW TO TAKE CombiNERV?
FOR HOW LONG CAN COMBINERV BE TAKEN?
It is recommended to take CombiNERV® for at least two consecutive months for better efficacy and long-term results.
ARE THERE ANY SIDE EFFECTS?
Do not take CombiNERV® in case of overt hypersensitivity to one or more ingredients or any other component of this food supplement.
Do not take during pregnancy and lactation.
Do not administer to children under the age of 12.
Contains GLUTEN: product unsuited for patients with celiac disease. In rare cases lipoic acid can cause hypoglycaemia.
.
IS A DOCTOR'S PRESCRIPTION REQUIRED?
CombiNERV® is a food supplement therefore a prescription is not required.
CAN CombiNERV BE TAKEN WITH OTHER DRUGS?
CombiNERV® can be taken with other drugs without any side effects.
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